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Structural analysis of P450 AmphL from Streptomyces nodosus provides insights into substrate selectivity of polyene macrolide antibiotic biosynthetic P450s.
Amaya, Jose A; Lamb, David C; Kelly, Steven L; Caffrey, Patrick; Murarka, Vidhi C; Poulos, Thomas L.
Afiliação
  • Amaya JA; Departments of Molecular Biology and Biochemistry, Pharmaceutical Sciences, and Chemistry, University of California, Irvine, California, USA.
  • Lamb DC; Faculty of Health, Medicine and Life Sciences, Swansea University, Swansea, UK.
  • Kelly SL; Faculty of Health, Medicine and Life Sciences, Swansea University, Swansea, UK.
  • Caffrey P; School of Biomolecular and Biomedical Science, University College Dublin, Belfield, Dublin 4, Ireland.
  • Murarka VC; Departments of Molecular Biology and Biochemistry, Pharmaceutical Sciences, and Chemistry, University of California, Irvine, California, USA.
  • Poulos TL; Departments of Molecular Biology and Biochemistry, Pharmaceutical Sciences, and Chemistry, University of California, Irvine, California, USA. Electronic address: poulos@uci.edu.
J Biol Chem ; 298(4): 101746, 2022 04.
Article em En | MEDLINE | ID: mdl-35189143
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptomyces / Proteínas de Bactérias / Anfotericina B Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptomyces / Proteínas de Bactérias / Anfotericina B Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article