Randomized controlled clinical trial comparing guided bone regeneration of peri-implant defects with soft-type block versus particulate bone substitutes: Six-month results of hard-tissue changes.

ABSTRACT

AIM: To test whether soft-type block bone substitute used for guided bone regeneration (GBR) of peri-implant defects leads to a different dimension of the augmented hard tissue than particulate bone substitute. MATERIALS AND METHODS: In 40 patients, 40 two-piece dental implants were placed >2 months after tooth extraction. Following random allocation, 20 peri-implant bone dehiscences were grafted with a soft-type block made of synthetic biphasic calcium phosphate (BCP) + collagen and 20 bone dehiscences with particulate BCP. All the sites were covered with a collagen membrane stabilized with titanium pins. Immediately after wound closure and after 6 months, the horizontal dimension (HD) of the augmented hard tissue was measured at the level of implant shoulder using cone beam computed tomography. During re-entry at 6 months, the defect fill was clinically assessed. RESULTS: At 6 months, the median HD measured 1.15 mm (mean 1.31 mm) in the soft-block group and 0.93 mm (mean 1.05 mm) in the particulate group (p = .6). At 6 months, 7.1% of contained defects and 61.9% of non-contained defects showed an incomplete vertical defect fill. CONCLUSIONS: Soft-type block of BCP + collagen used for GBR of peri-implant defects did not differ from particulate BCP regarding the dimension of the augmented hard tissue after 6 months of healing.