Inverse-Designed Aid Lenses for Precise Correction of Color Vision Deficiency.
Nano Lett
; 22(5): 2094-2102, 2022 03 09.
Article
em En
| MEDLINE
| ID: mdl-35226508
ABSTRACT
Color vision deficiency (CVD) is a common ocular disorder affecting more than 300 million people on the earth. Although no clinical cure for the disorder currently exists, some specialized color filtering glasses/lenses based on dyes, metasurfaces, or nanocomposites have been employed for CVD management. However, as CVD patients usually diversify in their classification and severity, none of the current lenses provides a customized correction for various CVD patients, resulting in undesirable correction effects. Here, we present an inverse-designed approach for the precise correction of CVD. The wavelength shift of a patient's abnormal cone photoreceptors was measured to inversely design the best blocking wavelength and blocking rate of the lens. Then the customized aid lenses were fabricated using silica-coated gold nanoparticles with appropriate sizes and concentrations, verified by the simulated color vision and human tests. This study demonstrates the potential of the inverse-designed aid lenses in precise color filtering and customized CVD management.
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Texto completo:
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças Cardiovasculares
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Defeitos da Visão Cromática
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Nanocompostos
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Nanopartículas Metálicas
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article