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Diagnosis and management of neutropenia in children: The approach of the Study Group on Neutropenia and Marrow Failure Syndromes of the Pediatric Italian Hemato-Oncology Association (Associazione Italiana Emato-Oncologia Pediatrica - AIEOP).
Fioredda, Francesca; Onofrillo, Daniela; Farruggia, Piero; Barone, Angelica; Veltroni, Marinella; Notarangelo, Lucia Dora; Menna, Giuseppe; Russo, Giovanna; Martire, Baldassarre; Finocchi, Andrea; Verzegnassi, Federico; Bonanomi, Sonia; Ramenghi, Ugo; Pillon, Marta; Dufour, Carlo.
Afiliação
  • Fioredda F; Unit of Haematology, IRCCS - Istituto Giannina Gaslini, Genoa, Italy.
  • Onofrillo D; Pediatric Hematology and Oncology Unit, Department of Hematology, Spirito Santo Hospital, Pescara, Italy.
  • Farruggia P; Department of Pediatric Onco-Hematology, University Hospital, Parma, Italy.
  • Barone A; Pediatric Hematology and Oncology Unit, ARNAS (Azienda di Rilievo Nazionale ad Alta Specializzazione) Ospedale Civico, Palermo, Italy.
  • Veltroni M; Department of Pediatric Onco-Hematology, Meyer Children's Hospital, Florence, Italy.
  • Notarangelo LD; Oncology-Haematology and Bone Marrow Transplantation Unit, Children's Hospital, Brescia, Italy.
  • Menna G; AORN (Azienda Ospedaliera Rilievo Nazionale), Santobono Pausillipon, Naples, Italy.
  • Russo G; Pediatric Ematologi and Oncology Unit, Azienda Policlinico-Vittorio Emanuele, University of Catania, Catania, Italy.
  • Martire B; Unit of Pediatrics and Neonatology, "Monsignor Dimiccoli" Hospital, Barletta, Italy.
  • Finocchi A; Unit of Immune and Infectious Disease, University Department of Pediatrics DPUO, Children's Hospital Bambino Gesù, IRCCS, Rome, Italy.
  • Verzegnassi F; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
  • Bonanomi S; Institute of Maternal and Child Health, IRCCS Burlo Garofalo, Trieste, Italy.
  • Ramenghi U; Department of Pediatric Hematology, San Gerardo Hospital, Monza, Italy.
  • Pillon M; MBBM (Monza e Brianza per Bambino e Mamma) Foundation, Department of Pediatrics, University of Milano - Bicocca, Monza, Italy.
  • Dufour C; Department of Pediatric and Public Health Sciences, University of Torino, Turin, Italy.
Pediatr Blood Cancer ; 69(6): e29599, 2022 06.
Article em En | MEDLINE | ID: mdl-35253359
ABSTRACT
Neutropenia refers to a group of diseases characterized by a reduction in neutrophil levels below the recommended age threshold. The present study aimed to review the diagnosis and management of neutropenia, including a diagnostic toolkit and candidate underlying genes. This study also aimed to review the progress toward the definition of autoimmune and idiopathic neutropenia rising in infancy or in late childhood but without remission, and provide suggestions for efficient diagnostics, including indications for the bone marrow and genetic testing. The management and treatment protocols for common and unique presentations are also reviewed, providing evidence tailored to a single patient.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medula Óssea / Neutropenia Tipo de estudo: Diagnostic_studies / Guideline / Risk_factors_studies Limite: Child / Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medula Óssea / Neutropenia Tipo de estudo: Diagnostic_studies / Guideline / Risk_factors_studies Limite: Child / Humans País/Região como assunto: Europa Idioma: En Ano de publicação: 2022 Tipo de documento: Article