Your browser doesn't support javascript.
loading
Effect of Intramuscularly Administered Oxytetracycline or Enrofloxacin on Vancomycin-Resistant Enterococci, Extended Spectrum Beta-Lactamase- and Carbapenemase-Producing Enterobacteriaceae in Pigs.
González-Fandos, Elena; Martínez-Laorden, Alba; Abad-Fau, Ana; Sevilla, Eloisa; Bolea, Rosa; Serrano, María Jesús; Mitjana, Olga; Bonastre, Cristina; Laborda, Alicia; Falceto, María Victoria; Pagán, Rafael.
Afiliação
  • González-Fandos E; Department of Food Technology, CIVA Research Center, University of La Rioja, 26006 Logrono, Spain.
  • Martínez-Laorden A; Department of Food Technology, CIVA Research Center, University of La Rioja, 26006 Logrono, Spain.
  • Abad-Fau A; AgriFood Research Institute of Aragón-IA2, University of Zaragoza-CITA, 50013 Zaragoza, Spain.
  • Sevilla E; AgriFood Research Institute of Aragón-IA2, University of Zaragoza-CITA, 50013 Zaragoza, Spain.
  • Bolea R; AgriFood Research Institute of Aragón-IA2, University of Zaragoza-CITA, 50013 Zaragoza, Spain.
  • Serrano MJ; AgriFood Research Institute of Aragón-IA2, University of Zaragoza-CITA, 50013 Zaragoza, Spain.
  • Mitjana O; AgriFood Research Institute of Aragón-IA2, University of Zaragoza-CITA, 50013 Zaragoza, Spain.
  • Bonastre C; AgriFood Research Institute of Aragón-IA2, University of Zaragoza-CITA, 50013 Zaragoza, Spain.
  • Laborda A; AgriFood Research Institute of Aragón-IA2, University of Zaragoza-CITA, 50013 Zaragoza, Spain.
  • Falceto MV; AgriFood Research Institute of Aragón-IA2, University of Zaragoza-CITA, 50013 Zaragoza, Spain.
  • Pagán R; AgriFood Research Institute of Aragón-IA2, University of Zaragoza-CITA, 50013 Zaragoza, Spain.
Animals (Basel) ; 12(5)2022 Mar 01.
Article em En | MEDLINE | ID: mdl-35268191
ABSTRACT
Nowadays, there is a great concern about the prevalence of multidrug resistant Enterococcus spp. and Enterobacteriaceae in food-producing animals. The aim of this work was to evaluate the effect of oxytetracycline or enrofloxacin treatment on vancomycin-resistant enterococci (VRE), extended spectrum ß-lactamase (ESBL) and carbapenemase-producing Enterobacteriaceae in pigs. A total of 26 piglets were received and distributed in three groups. Group 1 was treated with enrofloxacin (N = 12), group 2 with oxytetracycline (N = 10) and group 3 did not receive any treatment (control group) (N = 4). A higher number of vancomycin-resistant E. faecium were recovered compared to E. faecalis. In the pigs treated with enrofloxacin, vancomycin resistant E. faecium was found in a higher percentage of animals than in the control group. ESBL-producing E. coli was not detected in rectal samples from control animals. However, it was detected in 17-20% of animals treated with oxytetracycline on days 6 to 17 and in 17-50% of the animals treated with enrofloxacin. Carbapenemase-producing E. coli was isolated in animals treated with oxytetracycline, but not in animals treated with enrofloxacin or in the control group. This study highlights that the use of oxytetracycline or enrofloxacin in food-producing animals could select ESBL and carbapenemase-producing E. coli. Further studies shall be needed to validate the results obtained, considering a more robust and extended experimental design.
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article