Advancing secondary structure characterization of monoclonal antibodies using Microfluidic Modulation Spectroscopy.

Ivancic, Valerie A; Lombardo, Holly L; Ma, Eugene; Wikström, Mats; Batabyal, Dipanwita

Ivancic, Valerie A; Lombardo, Holly L; Ma, Eugene; Wikström, Mats; Batabyal, Dipanwita.

Afiliação

Ivancic VA; Redshift BioAnalytics, Inc., Burlington, MA, 01803, United States. Electronic address: vivancic@redshiftbio.com.
Lombardo HL; Redshift BioAnalytics, Inc., Burlington, MA, 01803, United States.
Ma E; Redshift BioAnalytics, Inc., Burlington, MA, 01803, United States.
Wikström M; Amgen Inc., Higher Order Structure, Attribute Sciences, Thousand Oaks, CA, 91320, United States.
Batabyal D; Amgen Inc., Higher Order Structure, Attribute Sciences, Thousand Oaks, CA, 91320, United States. Electronic address: dbatabya@amgen.com.

Anal Biochem ; 646: 114629, 2022 06 01.

Article em En | MEDLINE | ID: mdl-35289286

Assuntos

Anticorpos Monoclonais; Microfluídica; Anticorpos Monoclonais/química; Estrutura Secundária de Proteína; Espectrofotometria Infravermelho

Palavras-chave

Acquisition parameters; Infrared spectroscopy; Microfluidic modulation frequency; Monoclonal antibodies; Secondary structure characterization

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microfluídica / Anticorpos Monoclonais Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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