Visible-Light-Promoted Intramolecular C-O Bond Formation via Csp3-H Functionalization: A Straightforward Synthetic Route to Biorelevant Dihydrofuro[3,2-c]chromenone Derivatives.

ABSTRACT

A photochemical method for the synthesis of functionalized dihydrofuro[3,2-c]chromenones via intramolecular Csp3-H cross-dehydrogenative oxygenation within a warfarin framework has been unearthed. Advantages of this protocol include abundant sunlight or low-energy visible light as the energy source, mild reaction conditions, and avoidance of metal catalysts.