Low dose radiation therapy attenuates ACE2 depression and inflammatory cytokines induction by COVID-19 viral spike protein in human bronchial epithelial cells.

Wen, Ke; Bai, Chenjun; Zhao, Hongling; Zhou, Pingkun; Gao, Shanshan; Guan, Hua; Song, Man

Wen, Ke; Bai, Chenjun; Zhao, Hongling; Zhou, Pingkun; Gao, Shanshan; Guan, Hua; Song, Man.

Afiliação

Wen K; Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, China.
Bai C; Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, China.
Zhao H; Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, China.
Zhou P; Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, China.
Gao S; Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, China.
Guan H; Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, China.
Song M; Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, China.

Int J Radiat Biol ; 98(10): 1532-1541, 2022.

Article em En | MEDLINE | ID: mdl-35319335

Assuntos

COVID-19; Lesão Pulmonar; Enzima de Conversão de Angiotensina 2; COVID-19/radioterapia; Citocinas/metabolismo; Células Epiteliais/metabolismo; Humanos; Interleucina-6/metabolismo; Lesão Pulmonar/metabolismo; Peptidil Dipeptidase A/metabolismo; SARS-CoV-2; Glicoproteína da Espícula de Coronavírus/metabolismo; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

ACE2; COVID-19; Low dose radiation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lesão Pulmonar / COVID-19 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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