CENP-B-mediated DNA loops regulate activity and stability of human centromeres.

Chardon, Florian; Japaridze, Aleksandre; Witt, Hannes; Velikovsky, Leonid; Chakraborty, Camellia; Wilhelm, Therese; Dumont, Marie; Yang, Wayne; Kikuti, Carlos; Gangnard, Stephane; Mace, Anne-Sophie; Wuite, Gijs; Dekker, Cees; Fachinetti, Daniele

Chardon, Florian; Japaridze, Aleksandre; Witt, Hannes; Velikovsky, Leonid; Chakraborty, Camellia; Wilhelm, Therese; Dumont, Marie; Yang, Wayne; Kikuti, Carlos; Gangnard, Stephane; Mace, Anne-Sophie; Wuite, Gijs; Dekker, Cees; Fachinetti, Daniele.

Afiliação

Chardon F; Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm, 75005 Paris, France.
Japaridze A; Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, the Netherlands.
Witt H; Department of Physics and Astronomy, LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV Amsterdam, the Netherlands.
Velikovsky L; Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm, 75005 Paris, France.
Chakraborty C; Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm, 75005 Paris, France.
Wilhelm T; Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm, 75005 Paris, France.
Dumont M; Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm, 75005 Paris, France.
Yang W; Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, the Netherlands.
Kikuti C; Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm, 75005 Paris, France.
Gangnard S; Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm, 75005 Paris, France.
Mace AS; Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm, 75005 Paris, France.
Wuite G; Department of Physics and Astronomy, LaserLaB Amsterdam, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV Amsterdam, the Netherlands.
Dekker C; Department of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, the Netherlands.
Fachinetti D; Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm, 75005 Paris, France. Electronic address: daniele.fachinetti@curie.fr.

Mol Cell ; 82(9): 1751-1767.e8, 2022 05 05.

Article em En | MEDLINE | ID: mdl-35320753

Assuntos

Centrômero; Proteínas Cromossômicas não Histona; Autoantígenos/genética; Autoantígenos/metabolismo; Centrômero/genética; Centrômero/metabolismo; Proteína Centromérica A/genética; Proteína Centromérica A/metabolismo; Cromatina; Proteínas Cromossômicas não Histona/genética; Proteínas Cromossômicas não Histona/metabolismo; DNA/genética; Humanos

Palavras-chave

AFM microscopy; CENP; DNA breaks; DNA compaction; DNA topology; centromere; chromosomes; genome stability; optical tweezers; secondary structures

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Cromossômicas não Histona / Centrômero Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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