The Binding of <i>Alpinia galanga</i> Oil and Its Nanoemulsion to Mammal GABA<sub>A</sub> Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform.

Khumpirapang, Nattakanwadee; Suknuntha, Krit; Wongrattanakamon, Pathomwat; Jiranusornkul, Supat; Anuchapreeda, Songyot; Wellendorph, Petrine; Müllertz, Anette; Rades, Thomas; Okonogi, Siriporn

The Binding of Alpinia galanga Oil and Its Nanoemulsion to Mammal GABA_A Receptors Using Rat Cortical Membranes and an In Silico Modeling Platform.

Khumpirapang, Nattakanwadee; Suknuntha, Krit; Wongrattanakamon, Pathomwat; Jiranusornkul, Supat; Anuchapreeda, Songyot; Wellendorph, Petrine; Müllertz, Anette; Rades, Thomas; Okonogi, Siriporn.

Afiliação

Khumpirapang N; Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok 65000, Thailand.
Suknuntha K; Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Songkhla 90112, Thailand.
Wongrattanakamon P; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Jiranusornkul S; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Anuchapreeda S; Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Wellendorph P; Research Center of Pharmaceutical Nanotechnology, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Müllertz A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.
Rades T; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.
Okonogi S; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.

Pharmaceutics ; 14(3)2022 Mar 16.

Article em En | MEDLINE | ID: mdl-35336025

Palavras-chave

Alpinia galanga; anesthetic pathway; binding assay; essential oil; mammal anesthesia; positive allosteric modulation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article