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Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.
Yin, Xianyong; Chan, Lap Sum; Bose, Debraj; Jackson, Anne U; VandeHaar, Peter; Locke, Adam E; Fuchsberger, Christian; Stringham, Heather M; Welch, Ryan; Yu, Ketian; Fernandes Silva, Lilian; Service, Susan K; Zhang, Daiwei; Hector, Emily C; Young, Erica; Ganel, Liron; Das, Indraniel; Abel, Haley; Erdos, Michael R; Bonnycastle, Lori L; Kuusisto, Johanna; Stitziel, Nathan O; Hall, Ira M; Wagner, Gregory R; Kang, Jian; Morrison, Jean; Burant, Charles F; Collins, Francis S; Ripatti, Samuli; Palotie, Aarno; Freimer, Nelson B; Mohlke, Karen L; Scott, Laura J; Wen, Xiaoquan; Fauman, Eric B; Laakso, Markku; Boehnke, Michael.
Afiliação
  • Yin X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Chan LS; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Bose D; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • VandeHaar P; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Locke AE; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, 63108, USA.
  • Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Stringham HM; Institute for Biomedicine, Eurac Research, Bolzano, 39100, Italy.
  • Welch R; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Yu K; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Fernandes Silva L; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Service SK; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland.
  • Zhang D; Center for Neurobehavioral Genetics, Jane and Terry Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, CA, 90024, USA.
  • Hector EC; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Young E; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
  • Ganel L; Department of Statistics, North Carolina State University, Raleigh, NC, 27695, USA.
  • Das I; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, 63108, USA.
  • Abel H; Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO, 63110, USA.
  • Erdos MR; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, 63108, USA.
  • Bonnycastle LL; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, 63108, USA.
  • Kuusisto J; Department of Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA.
  • Stitziel NO; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Hall IM; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Wagner GR; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland.
  • Kang J; McDonnell Genome Institute, Washington University School of Medicine, St Louis, MO, 63108, USA.
  • Morrison J; Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO, 63110, USA.
  • Burant CF; Department of Genetics, Washington University School of Medicine, St Louis, MO, 63110, USA.
  • Collins FS; Center for Genomic Health, Department of Genetics, Yale University, New Haven, CT, 06510, USA.
  • Ripatti S; Metabolon, Inc., Morrisville, NC, 27560, USA.
  • Freimer NB; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Mohlke KL; Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, 48109, USA.
  • Scott LJ; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, 48109, USA.
  • Wen X; Molecular Genetics Section, Center for Precision Health Research, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Fauman EB; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, 00290, Finland.
  • Laakso M; Department of Public Health, University of Helsinki, Helsinki, 00014, Finland.
  • Boehnke M; Broad Institute of MIT & Harvard, Cambridge, MA, 02142, USA.
Nat Commun ; 13(1): 1644, 2022 03 28.
Article em En | MEDLINE | ID: mdl-35347128
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Estudo de Associação Genômica Ampla Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Estudo de Associação Genômica Ampla Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans / Male País/Região como assunto: Europa Idioma: En Ano de publicação: 2022 Tipo de documento: Article