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Advances in monitoring for acute spinal cord injury: a narrative review of current literature.
Tsehay, Yohannes; Weber-Levine, Carly; Kim, Timothy; Chara, Alejandro; Alomari, Safwan; Awosika, Tolulope; Liu, Ann; Ehresman, Jeffrey; Lehner, Kurt; Hwang, Brian; Hersh, Andrew M; Suk, Ian; Curry, Eli; Aghabaglou, Fariba; Zeng, Yinuo; Manbachi, Amir; Theodore, Nicholas.
Afiliação
  • Tsehay Y; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Weber-Levine C; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Kim T; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Chara A; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Alomari S; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Awosika T; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Liu A; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Ehresman J; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Lehner K; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Hwang B; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Hersh AM; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Suk I; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Curry E; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Aghabaglou F; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Zeng Y; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA.
  • Manbachi A; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA; Mechanical Engineering and Electrical Engineering, Johns Hopkins University School of Medicine
  • Theodore N; Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287 USA. Electronic address: Theodore@jhmi.edu.
Spine J ; 22(8): 1372-1387, 2022 08.
Article em En | MEDLINE | ID: mdl-35351667
ABSTRACT
Spinal cord injury (SCI) is a devastating condition that affects about 17,000 individuals every year in the United States, with approximately 294,000 people living with the ramifications of the initial injury. After the initial primary injury, SCI has a secondary phase during which the spinal cord sustains further injury due to ischemia, excitotoxicity, immune-mediated damage, mitochondrial dysfunction, apoptosis, and oxidative stress. The multifaceted injury progression process requires a sophisticated injury-monitoring technique for an accurate assessment of SCI patients. In this narrative review, we discuss SCI monitoring modalities, including pressure probes and catheters, micro dialysis, electrophysiologic measures, biomarkers, and imaging studies. The optimal next-generation injury monitoring setup should include multiple modalities and should integrate the data to produce a final simplified assessment of the injury and determine markers of intervention to improve patient outcomes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traumatismos da Medula Espinal Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Traumatismos da Medula Espinal Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article