Carbon sources and pathways for citrate secreted by human prostate cancer cells determined by NMR tracing and metabolic modeling.

van Heijster, Frits H A; Breukels, Vincent; Jansen, Kees C F J; Schalken, Jack A; Heerschap, Arend

van Heijster, Frits H A; Breukels, Vincent; Jansen, Kees C F J; Schalken, Jack A; Heerschap, Arend.

Afiliação

van Heijster FHA; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Breukels V; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Jansen KCFJ; Department of Urology, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Schalken JA; Department of Urology, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Heerschap A; Department of Radiology and Nuclear Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.

Proc Natl Acad Sci U S A ; 119(14): e2024357119, 2022 04 05.

Article em En | MEDLINE | ID: mdl-35353621

Assuntos

Biomarcadores Tumorais; Ácido Cítrico; Neoplasias da Próstata; Biomarcadores Tumorais/metabolismo; Carbono/metabolismo; Isótopos de Carbono; Citratos; Ácido Cítrico/metabolismo; Ciclo do Ácido Cítrico; Glucose/metabolismo; Humanos; Espectroscopia de Ressonância Magnética; Masculino; Neoplasias da Próstata/metabolismo

Palavras-chave

Krebs cycle; cancer; carbon-13; citrate; prostate

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Biomarcadores Tumorais / Ácido Cítrico Limite: Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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