Design, synthesis, and molecular modeling of heterodimer and inhibitors of &#945;-amylase as hypoglycemic agents.

Singh, Ved Prakash; Nidhar, Manisha; Yadav, Pratima; Kumar, Ranjeet; Sonker, Priyanka; Tewari, Ashish Kumar

Design, synthesis, and molecular modeling of heterodimer and inhibitors of α-amylase as hypoglycemic agents.

Singh, Ved Prakash; Nidhar, Manisha; Yadav, Pratima; Kumar, Ranjeet; Sonker, Priyanka; Tewari, Ashish Kumar.

Afiliação

Singh VP; Department of Industrial Chemistry, Mizoram University, Aizawl, 796009, India.
Nidhar M; Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India.
Yadav P; Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India.
Kumar R; Department of Chemistry, C.M.P. Degree College, University of Allahabad, Allahabad, Uttar Pradesh, 211002, India.
Sonker P; Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India.
Tewari AK; Department of Chemistry, Institute of Science, Banaras Hindu University, Varanasi, Uttar Pradesh, 221005, India. ashishtewarichem@gmail.com.

Mol Divers ; 27(1): 209-222, 2023 Feb.

Article em En | MEDLINE | ID: mdl-35357619

Assuntos

Antioxidantes; Hipoglicemiantes; Hipoglicemiantes/química; Simulação de Acoplamento Molecular; Antioxidantes/farmacologia; alfa-Amilases/química; PPAR gama; Estrutura Molecular; Relação Estrutura-Atividade

Palavras-chave

Antioxidant activity; Heterodimer; Molecular modeling; PPARÎ³; α-amylase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hipoglicemiantes / Antioxidantes Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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