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Anetumab ravtansine versus vinorelbine in patients with relapsed, mesothelin-positive malignant pleural mesothelioma (ARCS-M): a randomised, open-label phase 2 trial.
Kindler, Hedy L; Novello, Silvia; Bearz, Alessandra; Ceresoli, Giovanni L; Aerts, Joachim G J V; Spicer, James; Taylor, Paul; Nackaerts, Kristiaan; Greystoke, Alastair; Jennens, Ross; Calabrò, Luana; Burgers, Jacobus A; Santoro, Armando; Cedrés, Susana; Serwatowski, Piotr; Ponce, Santiago; Van Meerbeeck, Jan P; Nowak, Anna K; Blumenschein, George; Siegel, Jonathan M; Kasten, Linda; Köchert, Karl; Walter, Annette O; Childs, Barrett H; Elbi, Cem; Hassan, Raffit; Fennell, Dean A.
Afiliação
  • Kindler HL; Section of Hematology/Oncology, University of Chicago, Chicago, IL, USA. Electronic address: hkindler@medicine.bsd.uchicago.edu.
  • Novello S; Department of Oncology, University of Turin, Orbassano, Turin, Italy.
  • Bearz A; Department of Medical Oncology and Immune-Related Cancers, CRO-IRCCS Centro di Riferimento Oncologico di Aviano, Aviano, Italy.
  • Ceresoli GL; Department of Medical Oncology, Oncology Unit, Cliniche Humanitas Gavazzeni, Bergamo, Italy.
  • Aerts JGJV; Department of Pulmonary Medicine, Erasmus MC Cancer Centre, Rotterdam, Netherlands.
  • Spicer J; Comprehensive Cancer Centre, King's College London, London, UK.
  • Taylor P; Department of Medical Oncology, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, UK.
  • Nackaerts K; Laboratory of Respiratory Diseases and Thoracic Surgery, Department of Chronic Diseases and Metabolism, Universitair Ziekenhuis Leuven, KU Leuven, Leuven, Belgium.
  • Greystoke A; Department of Medical Oncology, Northern Centre for Cancer Care, Newcastle upon Tyne, UK.
  • Jennens R; Epworth Cancer Services Clinical Institute, Epworth Healthcare, Richmond, VIC, Australia.
  • Calabrò L; Department of Oncology, Center for Immuno-Oncology, University Hospital of Siena, Siena, Italy.
  • Burgers JA; Department of Thoracic Oncology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands.
  • Santoro A; Humanitas University, Milan, Italy; Department of Medical Oncology and Hematology, IRCCS Humanitas Research Hospital, Humanitas Cancer Center, Milan, Italy.
  • Cedrés S; Department of Medical Oncology, University Hospital Vall d'Hebron, Barcelona, Spain.
  • Serwatowski P; Department of Medical Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Ponce S; Department of Medical Oncology, Hospital Universitario 12 de Octubre, Madrid, Spain.
  • Van Meerbeeck JP; Department of Thoracic Oncology, Antwerp University and University Hospital and European Reference Network for Rare or Low Prevalence Complex Disease (ERN-LUNG), Antwerp, Belgium.
  • Nowak AK; Medical School, University of Western Australia, Perth, WA, Australia; National Centre for Asbestos Related Diseases, Institute for Respiratory Health, Perth, WA, Australia.
  • Blumenschein G; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Siegel JM; Clinical Statistics Oncology, Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Kasten L; Statistics, Syneos Health Clinical Solutions, Morrisville, NC, USA.
  • Köchert K; Biomarker and Data Insights, Bayer AG Pharma, Berlin, Germany.
  • Walter AO; Translational Medicine Oncology, Bayer AG Pharma, Berlin, Germany.
  • Childs BH; Oncology Development, Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Elbi C; Global Clinical Development, Oncology, Bayer HealthCare Pharmaceuticals, Whippany, NJ, USA.
  • Hassan R; Department of Thoracic and GI Malignancies, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
  • Fennell DA; Leicester Cancer Research Centre, University of Leicester and University Hospitals of Leicester NHS Trust, Leicester, UK. Electronic address: df132@leicester.ac.uk.
Lancet Oncol ; 23(4): 540-552, 2022 04.
Article em En | MEDLINE | ID: mdl-35358455

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoconjugados / Mesotelioma Maligno Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoconjugados / Mesotelioma Maligno Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article