Alkyl organophosphate flame retardants (OPFRs) induce lung inflammation and aggravate OVA-simulated asthmatic response via the NF-ÐºB signaling pathway.

Meng, Yuan; Xu, Xiaojuan; Xie, Guangming; Zhang, Yunwei; Chen, Shiyan; Qiu, Yanling; Zhu, Zhiliang; Zhang, Hua; Yin, Daqiang

Meng, Yuan; Xu, Xiaojuan; Xie, Guangming; Zhang, Yunwei; Chen, Shiyan; Qiu, Yanling; Zhu, Zhiliang; Zhang, Hua; Yin, Daqiang.

Afiliação

Meng Y; Key Laboratory of Yangtze River Water Environment, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, 1239 Siping Road, Shanghai 200092, China.
Xu X; Department of Pathology and Pathophysiology, Tongji University School of Medicine, Shanghai 200092, China.
Xie G; Tongji University School of Medicine, Shanghai 200092, China.
Zhang Y; Tongji University School of Medicine, Shanghai 200092, China.
Chen S; Key Laboratory of Yangtze River Water Environment, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, 1239 Siping Road, Shanghai 200092, China.
Qiu Y; Key Laboratory of Yangtze River Water Environment, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, 1239 Siping Road, Shanghai 200092, China. Electronic address: ylqiu@tongji.edu.cn.
Zhu Z; Key Laboratory of Yangtze River Water Environment, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, 1239 Siping Road, Shanghai 200092, China.
Zhang H; Key Laboratory of Yangtze River Water Environment, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, 1239 Siping Road, Shanghai 200092, China.
Yin D; Key Laboratory of Yangtze River Water Environment, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China; Shanghai Institute of Pollution Control and Ecological Security, 1239 Siping Road, Shanghai 200092, China.

Environ Int ; 163: 107209, 2022 05.

Article em En | MEDLINE | ID: mdl-35358787

Assuntos

Asma; Retardadores de Chama; Pneumonia; Animais; Asma/induzido quimicamente; Retardadores de Chama/toxicidade; Camundongos; NF-kappa B; Organofosfatos/toxicidade; Ovalbumina; Fosfatidilinositol 3-Quinases; Transdução de Sinais

Palavras-chave

Alkyl OPFRs; Asthma; Inflammation; Oxidative stress; Pulmonary toxicity

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia / Asma / Retardadores de Chama Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google