Möglicher Einfluss von Viren auf die Ausbreitung von Proteinaggregaten.
Biospektrum (Heidelb)
; 28(2): 162-164, 2022.
Article
em De
| MEDLINE
| ID: mdl-35369113
ABSTRACT
Neurodegenerative diseases are associated with misfolding of proteins into highly-ordered amyloid fibrils. These protein aggregates can be transmitted to other cells in which they induce aggregation of proteins of the same kind. Mechanisms of intercellular transfer include direct cell contact or transfer of aggregates within extracellular vesicles. Recent research suggests that viral proteins can increase the intercellular spreading of protein aggregation by promoting the required membrane interactions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
De
Ano de publicação:
2022
Tipo de documento:
Article