Abietane diterpenoids with neuroprotective activities from Phlegmariurus carinatus.
Nat Prod Res
; 36(23): 6006-6011, 2022 Dec.
Article
em En
| MEDLINE
| ID: mdl-35369804
ABSTRACT
Two new abietane diterpenoids, phlecarinatone A (1) and phlecarinatone B (2), along with two known analogues (3 and 4), were isolated from Phlegmariurus carinatus. The structures of 1 - 4 were unambiguously elucidated by comprehensive spectroscopic analyses. Abietane diterpenoids were isolated from the plant for the first time. All isolates were tested for their neuroprotective activities against H2O2-induced SH-SY5Y cells injury, and compound 2 showed moderate effect at the concentrations ranging from 5 â¼ 20 µM in vitro assay.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lycopodiaceae
/
Neuroblastoma
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article