SPCS: a spatial and pattern combined smoothing method for spatial transcriptomic expression.

Liu, Yusong; Wang, Tongxin; Duggan, Ben; Sharpnack, Michael; Huang, Kun; Zhang, Jie; Ye, Xiufen; Johnson, Travis S

Liu, Yusong; Wang, Tongxin; Duggan, Ben; Sharpnack, Michael; Huang, Kun; Zhang, Jie; Ye, Xiufen; Johnson, Travis S.

Afiliação

Liu Y; College of Intelligent Systems Science and Engineering, Harbin Engineering University, Harbin, Heilongjiang 150001, China.
Wang T; Department of Computer Science, Indiana University Bloomington, Bloomington, IN 47408, USA.
Duggan B; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Sharpnack M; Department of Pathology, University of California San Francisco, San Francisco, CA 94143, USA.
Huang K; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Zhang J; Regenstrief Institute, Indianapolis, IN 46202, USA.
Ye X; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Johnson TS; College of Intelligent Systems Science and Engineering, Harbin Engineering University, Harbin, Heilongjiang 150001, China.

Brief Bioinform ; 23(3)2022 05 13.

Article em En | MEDLINE | ID: mdl-35380614

Assuntos

Análise de Célula Única; Transcriptoma; Perfilação da Expressão Gênica/métodos; RNA; Análise de Sequência de RNA/métodos; Análise de Célula Única/métodos; Software

Palavras-chave

k-nearest neighbors; dorsolateral prefrontal cortex; high-grade serous ovarian cancer; imputation; pancreatic ductal adenocarcinoma; spatial transcriptomics; tissue region partition; two-factor expression smoothing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Análise de Célula Única / Transcriptoma Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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