Therapeutic correction of hemophilia A by transplantation of hPSC-derived liver sinusoidal endothelial cell progenitors.

Gage, Blair K; Merlin, Simone; Olgasi, Cristina; Follenzi, Antonia; Keller, Gordon M

Gage, Blair K; Merlin, Simone; Olgasi, Cristina; Follenzi, Antonia; Keller, Gordon M.

Afiliação

Gage BK; McEwen Stem Cell Institute, University Health Network, Toronto, ON M5G1L7, Canada. Electronic address: blair.gage@uhnresearch.ca.
Merlin S; Department of Health Sciences, School of Medicine, University of Piemonte Orientale, 28100 Novara, Italy.
Olgasi C; Department of Health Sciences, School of Medicine, University of Piemonte Orientale, 28100 Novara, Italy.
Follenzi A; Department of Health Sciences, School of Medicine, University of Piemonte Orientale, 28100 Novara, Italy.
Keller GM; McEwen Stem Cell Institute, University Health Network, Toronto, ON M5G1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G1L7, Canada. Electronic address: gordon.keller@uhnresearch.ca.

Cell Rep ; 39(1): 110621, 2022 04 05.

Article em En | MEDLINE | ID: mdl-35385743

Assuntos

Células Progenitoras Endoteliais; Hemofilia A; Células-Tronco Pluripotentes; Animais; Hemofilia A/genética; Hemofilia A/terapia; Hepatócitos; Fígado; Camundongos

Palavras-chave

CP: Cell biology; CP: Stem cell research; FVIII; cell therapy; competitive transplantation; hPSCs; hemophilia A; liver sinusoidal endothelial cells; mesoderm; venous endothelial cell

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes / Células Progenitoras Endoteliais / Hemofilia A Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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