Synthesis of 5-unsubstituted dihydropyrimidinone-4-carboxylates from deep eutectic mixtures.

ABSTRACT

A facile one-pot synthesis of 5-unsubstituted dihydropyrimidinones from ß,γ-unsaturated ketoesters in low melting ʟ-(+)-tartaric acid-N,N-dimethylurea mixtures is reported. This solvent-free method is very general and provides easy access to 5-unsubstituted dihydropyrimidinone-4-carboxylate derivatives in good yields.