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Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors.
Horton, John R; Pathuri, Sarath; Wong, Kristen; Ren, Ren; Rueda, Lourdes; Fosbenner, David T; Heerding, Dirk A; McCabe, Michael T; Pappalardi, Melissa B; Zhang, Xing; King, Bryan W; Cheng, Xiaodong.
Afiliação
  • Horton JR; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Pathuri S; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Wong K; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Ren R; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Rueda L; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Fosbenner DT; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Heerding DA; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • McCabe MT; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Pappalardi MB; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA.
  • Zhang X; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • King BW; Cancer Epigenetics Research Unit, Oncology, GlaxoSmithKline, Collegeville, PA 19426, USA. Electronic address: bryan.w.king@gsk.com.
  • Cheng X; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: xcheng5@mdanderson.org.
Structure ; 30(6): 793-802.e5, 2022 06 02.
Article em En | MEDLINE | ID: mdl-35395178
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metilação de DNA / DNA (Citosina-5-)-Metiltransferases Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metilação de DNA / DNA (Citosina-5-)-Metiltransferases Idioma: En Ano de publicação: 2022 Tipo de documento: Article