Potent necrosis effect of methanethiol mediated by METTL7B enzyme bioactivation mechanism in 16HBE cell.

Lei, Jinting; Li, Guiying; Yu, Hang; An, Taicheng

Lei, Jinting; Li, Guiying; Yu, Hang; An, Taicheng.

Afiliação

Lei J; Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Institute of Environmental Health and Pollution control, Guangdong University of Technology, Guangzhou 510006, China.
Li G; Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Institute of Environmental Health and Pollution control, Guangdong University of Technology, Guangzhou 510006, China; Guangzhou Key Laboratory
Yu H; Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Institute of Environmental Health and Pollution control, Guangdong University of Technology, Guangzhou 510006, China; Guangzhou Key Laboratory
An T; Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Institute of Environmental Health and Pollution control, Guangdong University of Technology, Guangzhou 510006, China; Guangzhou Key Laboratory

Ecotoxicol Environ Saf ; 236: 113486, 2022 May 01.

Article em En | MEDLINE | ID: mdl-35397445

Assuntos

Brônquios; Proteínas de Transporte; Metiltransferases; Compostos de Sulfidrila; Brônquios/efeitos dos fármacos; Brônquios/enzimologia; Brônquios/patologia; Proteínas de Transporte/metabolismo; Ativação Enzimática; Células Epiteliais/efeitos dos fármacos; Células Epiteliais/enzimologia; Células Epiteliais/patologia; Humanos; Metiltransferases/genética; Metiltransferases/metabolismo; Necrose; Espécies Reativas de Oxigênio/metabolismo; Compostos de Sulfidrila/farmacologia

Palavras-chave

16HBE cells; Bioactivation; Cell necrosis; In vitro metabolism; Methanethiol

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Sulfidrila / Brônquios / Proteínas de Transporte / Metiltransferases Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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