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Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity.
Maruhashi, Takumi; Sugiura, Daisuke; Okazaki, Il-Mi; Shimizu, Kenji; Maeda, Takeo K; Ikubo, Jun; Yoshikawa, Harunori; Maenaka, Katsumi; Ishimaru, Naozumi; Kosako, Hidetaka; Takemoto, Tatsuya; Okazaki, Taku.
Afiliação
  • Maruhashi T; Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo 113-0032, Japan.
  • Sugiura D; Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo 113-0032, Japan.
  • Okazaki IM; Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo 113-0032, Japan; Division of Immune Regulation, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.
  • Shimizu K; Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo 113-0032, Japan.
  • Maeda TK; Division of Immune Regulation, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.
  • Ikubo J; Division of Immune Regulation, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.
  • Yoshikawa H; Division of Cell Signaling, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.
  • Maenaka K; Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan.
  • Ishimaru N; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima 770-8504, Japan.
  • Kosako H; Division of Cell Signaling, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.
  • Takemoto T; Laboratory of Embryology, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan.
  • Okazaki T; Laboratory of Molecular Immunology, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo 113-0032, Japan; Division of Immune Regulation, Institute of Advanced Medical Sciences, Tokushima University, Tokushima 770-8503, Japan. Electronic address: tokazaki@iqb.u-tokyo.ac.jp.
Immunity ; 55(5): 912-924.e8, 2022 05 10.
Article em En | MEDLINE | ID: mdl-35413245
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Antígenos de Histocompatibilidade Classe II / Antígenos CD / Autoimunidade / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfócitos T / Antígenos de Histocompatibilidade Classe II / Antígenos CD / Autoimunidade / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article