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A point mutation in the nucleotide exchange factor eIF2B constitutively activates the integrated stress response by allosteric modulation.
Boone, Morgane; Wang, Lan; Lawrence, Rosalie E; Frost, Adam; Walter, Peter; Schoof, Michael.
Afiliação
  • Boone M; Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, United States.
  • Wang L; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.
  • Lawrence RE; Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, United States.
  • Frost A; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.
  • Walter P; Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, United States.
  • Schoof M; Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, United States.
Elife ; 112022 04 13.
Article em En | MEDLINE | ID: mdl-35416150
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Iniciação 2 em Eucariotos / Fator de Iniciação 2B em Eucariotos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Iniciação 2 em Eucariotos / Fator de Iniciação 2B em Eucariotos Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article