CLOCK regulates Drp1 mRNA stability and mitochondrial homeostasis by interacting with PUF60.

Xu, Lirong; Lin, Jiaxin; Liu, Yutong; Hua, Bingxuan; Cheng, Qianyun; Lin, Changpo; Yan, Zuoqin; Wang, Yaping; Sun, Ning; Qian, Ruizhe; Lu, Chao

Xu, Lirong; Lin, Jiaxin; Liu, Yutong; Hua, Bingxuan; Cheng, Qianyun; Lin, Changpo; Yan, Zuoqin; Wang, Yaping; Sun, Ning; Qian, Ruizhe; Lu, Chao.

Afiliação

Xu L; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
Lin J; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
Liu Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
Hua B; Department of Orthopedics, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Cheng Q; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
Lin C; Institute of Vascular Surgery, Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Yan Z; Department of Orthopedics, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Wang Y; Department of Surgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Sun N; Wuxi School of Medicine, Jiangnan University, Jiangsu 214122, China. Electronic address: sunning@jiangnan.edu.cn.
Qian R; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China. Electronic address: rzqian@shmu.edu.cn.
Lu C; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China. Electronic address: luchao@shmu.edu.cn.

Cell Rep ; 39(2): 110635, 2022 04 12.

Article em En | MEDLINE | ID: mdl-35417690

Assuntos

Proteínas CLOCK; Relógios Circadianos; Animais; Proteínas CLOCK/genética; Proteínas CLOCK/metabolismo; Relógios Circadianos/genética; Homeostase/genética; Camundongos; Mitocôndrias/metabolismo; Dinâmica Mitocondrial; Estabilidade de RNA

Palavras-chave

CP: Metabolism; CP: Molecular biology; Clock; Drp1; PUF60; mRNA stability; mitochondrial fission

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas CLOCK / Relógios Circadianos Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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