Your browser doesn't support javascript.
loading
Development of Optical Biosensor for the Detection of Glutamine in Human Biofluids Using Merocyanine Dye.
Sathya, Vijayakumar; Deepa, Appadurai; Sangeetha, Lakshmi Kandhan; Srinivasadesikan, Venkatesan; Lee, Shyi-Long; Padmini, Vediappen.
Afiliação
  • Sathya V; Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, 625021, Tamilnadu, India.
  • Deepa A; Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, 625021, Tamilnadu, India.
  • Sangeetha LK; Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, 625021, Tamilnadu, India.
  • Srinivasadesikan V; Division of Chemistry, Department of Sciences and Humanities, Vignan's Foundation for Science, Technology and Research, Vadlamudi, Guntur, 522 213, Andhra Pradesh, India.
  • Lee SL; Department of Chemistry and Biochemistry, National Chung-Cheng University, Chia-Yi, 621, Taiwan.
  • Padmini V; Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, 625021, Tamilnadu, India. padmini.chem@mkuniversity.org.
J Fluoresc ; 32(4): 1389-1396, 2022 Jul.
Article em En | MEDLINE | ID: mdl-35420326
ABSTRACT
Merocyanine dye based fluorescent organic compound has been synthesized for the detection of glutamine. The probe showed remarkable fluorescent intensity with glutamine through ICT (Intermolecular Charge Transfer Mechanism). Hence, it is tested for the detection of glutamine using colorimetric and fluorimetric techniques in physiological and neutral pH (7.2). Under optimized experimental conditions, the probe detects glutamine selectively among other interfering biomolecules. The probe has showed a LOD (lower limit of detection) of 9.6 × 10-8 mol/L at the linear range 0-180 µM towards glutamine. The practical application of the probe is successfully tested in human biofluids.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Corantes Fluorescentes Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Técnicas Biossensoriais / Corantes Fluorescentes Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article