Generation of Tumor-Specific Cytotoxic T Cells From Blood <i>via In Vitro</i> Expansion Using Autologous Dendritic Cells Pulsed With Neoantigen-Coupled Microbeads.

Kiessling, Adela; Ramanathan, Keerthana; Nilsson, Ola B; Notari, Luigi; Renken, Stefanie; Kiessling, Rolf; Grönlund, Hans; Wickström, Stina L

Generation of Tumor-Specific Cytotoxic T Cells From Blood via In Vitro Expansion Using Autologous Dendritic Cells Pulsed With Neoantigen-Coupled Microbeads.

Kiessling, Adela; Ramanathan, Keerthana; Nilsson, Ola B; Notari, Luigi; Renken, Stefanie; Kiessling, Rolf; Grönlund, Hans; Wickström, Stina L.

Afiliação

Kiessling A; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Ramanathan K; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Nilsson OB; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Notari L; NEOGAP Therapeutics AB, Stockholm, Sweden.
Renken S; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Kiessling R; NEOGAP Therapeutics AB, Stockholm, Sweden.
Grönlund H; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Wickström SL; Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

Front Oncol ; 12: 866763, 2022.

Article em En | MEDLINE | ID: mdl-35433456

Palavras-chave

autologous tumor recognition; dendritic cell-mediated activation; neoantigen; personalized cancer immunotherapy; tumor-specific antigens

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Ano de publicação: 2022 Tipo de documento: Article