Initial screening by immunohistochemistry is effective in universal screening for Lynch syndrome in endometrial cancer patients: a prospective observational study.

Tsuruta, Tomohiko; Todo, Yukiharu; Yamada, Ryutaro; Kuwahara, Ken; Kurosu, Hiroyuki; Minowa, Kaoru; Minoura, Yuko; Minobe, Shinichiro; Suzuki, Hiroaki; Kato, Hidenori

Tsuruta, Tomohiko; Todo, Yukiharu; Yamada, Ryutaro; Kuwahara, Ken; Kurosu, Hiroyuki; Minowa, Kaoru; Minoura, Yuko; Minobe, Shinichiro; Suzuki, Hiroaki; Kato, Hidenori.

Afiliação

Tsuruta T; Department of Perinatology and Gynecology, Kagawa University Graduate School of Medicine, Kagawa, Japan.
Todo Y; Division of Gynecologic Oncology, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan.
Yamada R; Division of Gynecologic Oncology, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan.
Kuwahara K; Division of Gynecologic Oncology, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan.
Kurosu H; Division of Pathology, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan.
Minowa K; Division of Gynecologic Oncology, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan.
Minoura Y; Division of Gynecologic Oncology, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan.
Minobe S; Division of Gynecologic Oncology, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan.
Suzuki H; Division of Gynecologic Oncology, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan.
Kato H; Division of Pathology, National Hospital Organization, Hokkaido Cancer Center, Sapporo, Japan.

Jpn J Clin Oncol ; 52(7): 752-758, 2022 07 08.

Article em En | MEDLINE | ID: mdl-35438162

Assuntos

Neoplasias Colorretais Hereditárias sem Polipose; Neoplasias do Endométrio; Neoplasias Colorretais Hereditárias sem Polipose/complicações; Neoplasias Colorretais Hereditárias sem Polipose/diagnóstico; Neoplasias Colorretais Hereditárias sem Polipose/genética; Reparo de Erro de Pareamento de DNA/genética; Detecção Precoce de Câncer/métodos; Neoplasias do Endométrio/diagnóstico; Neoplasias do Endométrio/genética; Neoplasias do Endométrio/patologia; Feminino; Humanos; Imuno-Histoquímica; Instabilidade de Microssatélites; Endonuclease PMS2 de Reparo de Erro de Pareamento/genética; Proteína 1 Homóloga a MutL/genética; Proteína 2 Homóloga a MutS/genética; Proteína 2 Homóloga a MutS/metabolismo; Estudos Prospectivos

Palavras-chave

Lynch syndrome; endometrial cancer; mismatch repair gene; prospective observational study; universal screening

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais Hereditárias sem Polipose / Neoplasias do Endométrio Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Female / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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