Calcitriol Supplementation Protects Against Apoptosis and Alleviates the Severity of Abdominal Aortic Aneurysm Induced by Angiotensin II and Anti-TGFß.

Jreije, Afaf; Medlej-Hashim, Myrna; Hajal, Joelle; Saliba, Youakim; Chacar, Stephanie; Fares, Nassim; Khouzami, Lara

Jreije, Afaf; Medlej-Hashim, Myrna; Hajal, Joelle; Saliba, Youakim; Chacar, Stephanie; Fares, Nassim; Khouzami, Lara.

Afiliação

Jreije A; Laboratoire de Recherche en Physiologie Et Physiopathologie, Faculté de Médecine, Pôle Technologie Santé, Université Saint Joseph, Beirut, Lebanon.
Medlej-Hashim M; Cellular and Molecular Physiopathologies (CAMP) Laboratory, Faculty of Sciences II, Lebanese University, Fanar, Lebanon.
Hajal J; Cellular and Molecular Physiopathologies (CAMP) Laboratory, Faculty of Sciences II, Lebanese University, Fanar, Lebanon.
Saliba Y; Laboratoire de Recherche en Physiologie Et Physiopathologie, Faculté de Médecine, Pôle Technologie Santé, Université Saint Joseph, Beirut, Lebanon.
Chacar S; Laboratoire de Recherche en Physiologie Et Physiopathologie, Faculté de Médecine, Pôle Technologie Santé, Université Saint Joseph, Beirut, Lebanon.
Fares N; Laboratoire de Recherche en Physiologie Et Physiopathologie, Faculté de Médecine, Pôle Technologie Santé, Université Saint Joseph, Beirut, Lebanon.
Khouzami L; Laboratoire de Recherche en Physiologie Et Physiopathologie, Faculté de Médecine, Pôle Technologie Santé, Université Saint Joseph, Beirut, Lebanon. nassim.fares@usj.edu.lb.

J Cardiovasc Transl Res ; 15(6): 1340-1351, 2022 12.

Article em En | MEDLINE | ID: mdl-35445935

Assuntos

Aneurisma da Aorta Abdominal; Calcitriol; Animais; Camundongos; Angiotensina II/efeitos adversos; Aorta Abdominal; Aneurisma da Aorta Abdominal/induzido quimicamente; Aneurisma da Aorta Abdominal/diagnóstico por imagem; Aneurisma da Aorta Abdominal/prevenção & controle; Apoptose; Calcitriol/farmacologia; Calcitriol/uso terapêutico; Suplementos Nutricionais; Modelos Animais de Doenças; Camundongos Endogâmicos C57BL; Camundongos Knockout; Fator 2 Relacionado a NF-E2/metabolismo; Fator de Crescimento Transformador beta/antagonistas & inibidores

Palavras-chave

Abdominal aortic aneurysm; Calcitriol; Caspase; Cu/Zn-SOD; Nrf2; Vitamin D deficiency

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Calcitriol / Aneurisma da Aorta Abdominal Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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