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Relationship between the risk of idiosyncratic drug toxicity and formation and degradation profiles of acyl-glucuronide metabolites of nonsteroidal anti-inflammatory drugs in rat liver microsomes.
Shimada, Hiroaki; Ikuta, Hiroyuki; Kumazawa, Keisuke; Nomi, Manato; Shiojiri, Mayumi; Kawase, Atsushi; Iwaki, Masahiro.
Afiliação
  • Shimada H; Department of Pharmacy, Faculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan.
  • Ikuta H; Department of Pharmacy, Faculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan.
  • Kumazawa K; Department of Pharmacy, Faculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan.
  • Nomi M; Department of Pharmacy, Faculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan.
  • Shiojiri M; Department of Pharmacy, Faculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan.
  • Kawase A; Department of Pharmacy, Faculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan.
  • Iwaki M; Department of Pharmacy, Faculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-osaka, Osaka 577-8502, Japan; Pharmaceutical Research and Technology Institute, Kindai University, Osaka 577-8502, Japan; Antiaging Center, Kindai University, Osaka 577-8502, Japan. Electronic address: iwaki@phar.
Eur J Pharm Sci ; 174: 106193, 2022 Jul 01.
Article em En | MEDLINE | ID: mdl-35447304
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glucuronídeos / Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glucuronídeos / Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article