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New aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the hydroxytriazole scaffold.
Pippione, Agnese Chiara; Kilic-Kurt, Zühal; Kovachka, Sandra; Sainas, Stefano; Rolando, Barbara; Denasio, Enrica; Pors, Klaus; Adinolfi, Salvatore; Zonari, Daniele; Bagnati, Renzo; Lolli, Marco Lucio; Spyrakis, Francesca; Oliaro-Bosso, Simonetta; Boschi, Donatella.
Afiliação
  • Pippione AC; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy.
  • Kilic-Kurt Z; Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara, Turkey.
  • Kovachka S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy.
  • Sainas S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy.
  • Rolando B; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy.
  • Denasio E; Institute of Cancer Therapeutics, Faculty of Life Sciences, University of Bradford, West Yorkshire, BD7 1DP, UK.
  • Pors K; Institute of Cancer Therapeutics, Faculty of Life Sciences, University of Bradford, West Yorkshire, BD7 1DP, UK.
  • Adinolfi S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy.
  • Zonari D; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy.
  • Bagnati R; Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, via Mario Negri 2, 20156, Milan, Italy.
  • Lolli ML; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy.
  • Spyrakis F; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy. Electronic address: francesca.spyrakis@unito.it.
  • Oliaro-Bosso S; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy. Electronic address: simona.oliaro@unito.it.
  • Boschi D; Department of Science and Drug Technology, University of Turin, via Pietro Giuria 9, 10125, Turin, Italy. Electronic address: donatella.boschi@unito.it.
Eur J Med Chem ; 237: 114366, 2022 Jul 05.
Article em En | MEDLINE | ID: mdl-35447434
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Neoplasias de Próstata Resistentes à Castração / Membro C3 da Família 1 de alfa-Ceto Redutase / Antineoplásicos Limite: Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores Enzimáticos / Neoplasias de Próstata Resistentes à Castração / Membro C3 da Família 1 de alfa-Ceto Redutase / Antineoplásicos Limite: Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article