Fucoxanthin Attenuates Free Fatty Acid-Induced Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism/Oxidative Stress/Inflammation via the AMPK/Nrf2/TLR4 Signaling Pathway.

Ye, Jiena; Zheng, Jiawen; Tian, Xiaoxiao; Xu, Baogui; Yuan, Falei; Wang, Bin; Yang, Zuisu; Huang, Fangfang

Ye, Jiena; Zheng, Jiawen; Tian, Xiaoxiao; Xu, Baogui; Yuan, Falei; Wang, Bin; Yang, Zuisu; Huang, Fangfang.

Afiliação

Ye J; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Zheng J; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Tian X; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Xu B; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Yuan F; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Wang B; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Yang Z; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Huang F; Zhejiang Provincial Engineering Technology Research Center of Marine Biomedical Products, School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.

Mar Drugs ; 20(4)2022 Mar 25.

Article em En | MEDLINE | ID: mdl-35447899

Assuntos

Hepatopatia Gordurosa não Alcoólica; Proteínas Quinases Ativadas por AMP/metabolismo; Animais; Ácidos Graxos não Esterificados/metabolismo; Inflamação/induzido quimicamente; Inflamação/tratamento farmacológico; Inflamação/metabolismo; Metabolismo dos Lipídeos; Fígado; Camundongos; Fator 2 Relacionado a NF-E2/metabolismo; Hepatopatia Gordurosa não Alcoólica/induzido quimicamente; Hepatopatia Gordurosa não Alcoólica/tratamento farmacológico; Hepatopatia Gordurosa não Alcoólica/metabolismo; Estresse Oxidativo; Transdução de Sinais; Receptor 4 Toll-Like/metabolismo; Xantofilas/metabolismo; Xantofilas/farmacologia

Palavras-chave

NAFLD; Toll-like receptor 4-mediated (TLR4); adenosine monophosphate-activated protein kinase (AMPK); fucoxanthin; nuclear factor erythroid-2-related factor 2-mediated (Nrf2)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatopatia Gordurosa não Alcoólica Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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