Discovery of 5-Aryl-2,4-diaminopyrimidine Compounds as Potent and Selective IRAK4 Inhibitors.

Chen, Yan; Singh, Rajinder; Lin, Nan; Taylor, Vanessa; Masuda, Esteban S; Payan, Donald G

Chen, Yan; Singh, Rajinder; Lin, Nan; Taylor, Vanessa; Masuda, Esteban S; Payan, Donald G.

Afiliação

Chen Y; Rigel Pharmaceuticals Inc., 1180 Veterans Boulevard, South San Francisco, California 94080, United States.
Singh R; Rigel Pharmaceuticals Inc., 1180 Veterans Boulevard, South San Francisco, California 94080, United States.
Lin N; Rigel Pharmaceuticals Inc., 1180 Veterans Boulevard, South San Francisco, California 94080, United States.
Taylor V; Rigel Pharmaceuticals Inc., 1180 Veterans Boulevard, South San Francisco, California 94080, United States.
Masuda ES; Rigel Pharmaceuticals Inc., 1180 Veterans Boulevard, South San Francisco, California 94080, United States.
Payan DG; Rigel Pharmaceuticals Inc., 1180 Veterans Boulevard, South San Francisco, California 94080, United States.

ACS Med Chem Lett ; 13(4): 714-719, 2022 Apr 14.

Article em En | MEDLINE | ID: mdl-35450353

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article