ABCB1 as a potential beneficial target of midostaurin in acute myeloid leukemia.

Sucha, Simona; Sorf, Ales; Svoren, Martin; Vagiannis, Dimitrios; Ahmed, Fahda; Visek, Benjamin; Ceckova, Martina

Sucha, Simona; Sorf, Ales; Svoren, Martin; Vagiannis, Dimitrios; Ahmed, Fahda; Visek, Benjamin; Ceckova, Martina.

Afiliação

Sucha S; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 50005 Hradec Kralove, Czech Republic.
Sorf A; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 50005 Hradec Kralove, Czech Republic.
Svoren M; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 50005 Hradec Kralove, Czech Republic.
Vagiannis D; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 50005 Hradec Kralove, Czech Republic.
Ahmed F; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 50005 Hradec Kralove, Czech Republic.
Visek B; 4th Department of Internal Medicine - Hematology, University Hospital Hradec Kralove, Sokolska 581, 50005 Hradec Kralove, Czech Republic.
Ceckova M; Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Kralove, Charles University, Akademika Heyrovskeho 1203, 50005 Hradec Kralove, Czech Republic. Electronic address: martina.ceckova@faf.cuni.cz.

Biomed Pharmacother ; 150: 112962, 2022 Jun.

Article em En | MEDLINE | ID: mdl-35462331

Assuntos

Subfamília B de Transportador de Cassetes de Ligação de ATP; Leucemia Mieloide Aguda; MicroRNAs; Estaurosporina; Subfamília B de Transportador de Cassetes de Ligação de ATP/genética; Subfamília B de Transportador de Cassetes de Ligação de ATP/metabolismo; Antraciclinas/farmacologia; Humanos; Leucemia Mieloide Aguda/tratamento farmacológico; Leucemia Mieloide Aguda/genética; Leucemia Mieloide Aguda/metabolismo; Leucócitos Mononucleares/efeitos dos fármacos; Leucócitos Mononucleares/metabolismo; MicroRNAs/genética; MicroRNAs/metabolismo; Mutação; Inibidores de Proteínas Quinases/farmacologia; Estaurosporina/análogos & derivados; Estaurosporina/farmacologia

Palavras-chave

ABCB1; Acute myeloid leukemia; FLT3; Midostaurin; Multidrug resistance; P-glycoprotein

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Estaurosporina / Subfamília B de Transportador de Cassetes de Ligação de ATP / MicroRNAs Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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