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Cell surface-tethered IL-12 repolarizes the tumor immune microenvironment to enhance the efficacy of adoptive T cell therapy.
Jones, Douglas S; Nardozzi, Jonathan D; Sackton, Katharine L; Ahmad, Gulzar; Christensen, Esben; Ringgaard, Lars; Chang, De-Kuan; Jaehger, Ditte E; Konakondla, Jacob V; Wiinberg, Martin; Stokes, Kate L; Pratama, Alvin; Sauer, Karsten; Andresen, Thomas L.
Afiliação
  • Jones DS; Repertoire Immune Medicines, Cambridge MA, USA.
  • Nardozzi JD; Repertoire Immune Medicines, Cambridge MA, USA.
  • Sackton KL; Repertoire Immune Medicines, Cambridge MA, USA.
  • Ahmad G; Repertoire Immune Medicines, Cambridge MA, USA.
  • Christensen E; Technical University of Denmark, Copenhagen, Denmark.
  • Ringgaard L; Technical University of Denmark, Copenhagen, Denmark.
  • Chang DK; Repertoire Immune Medicines, Cambridge MA, USA.
  • Jaehger DE; Technical University of Denmark, Copenhagen, Denmark.
  • Konakondla JV; Repertoire Immune Medicines, Cambridge MA, USA.
  • Wiinberg M; Technical University of Denmark, Copenhagen, Denmark.
  • Stokes KL; Repertoire Immune Medicines, Cambridge MA, USA.
  • Pratama A; Repertoire Immune Medicines, Cambridge MA, USA.
  • Sauer K; Repertoire Immune Medicines, Cambridge MA, USA.
  • Andresen TL; Repertoire Immune Medicines, Cambridge MA, USA.
Sci Adv ; 8(17): eabi8075, 2022 04 29.
Article em En | MEDLINE | ID: mdl-35476449
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-12 / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Interleucina-12 / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article