Asymptomatic carriers of the p.A53T SNCA mutation: Data from the PPMI study.
Parkinsonism Relat Disord
; 98: 72-74, 2022 05.
Article
em En
| MEDLINE
| ID: mdl-35490542
ABSTRACT
We assessed non motor characteristics of 12 asymptomatic p.A53T mutation carriers (A53T-AC) compared with 36 healthy controls (HC) enrolled in the Parkinson's Progression Markers Initiative (PPMI) study. Olfaction score was lower and anxiety was marginally more prevalent in A53T- AC. These findings suggest distinct prodromal features in this group of subjects.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Alfa-Sinucleína
/
Sintomas Prodrômicos
Limite:
Humans
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article