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Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human α2-macroglobulin.
Luque, Daniel; Goulas, Theodoros; Mata, Carlos P; Mendes, Soraia R; Gomis-Rüth, F Xavier; Castón, José R.
Afiliação
  • Luque D; Spanish National Microbiology Centre, Institute of Health Carlos III, 28220 Madrid, Spain.
  • Goulas T; Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona (IBMB-CSIC), 08028 Barcelona, Catalonia, Spain.
  • Mata CP; Department of Food Science and Nutrition, School of Agricultural Sciences, University of Thessaly, 43100 Karditsa, Greece.
  • Mendes SR; The Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom.
  • Gomis-Rüth FX; Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona (IBMB-CSIC), 08028 Barcelona, Catalonia, Spain.
  • Castón JR; Proteolysis Lab, Department of Structural Biology, Molecular Biology Institute of Barcelona (IBMB-CSIC), 08028 Barcelona, Catalonia, Spain.
Proc Natl Acad Sci U S A ; 119(19): e2200102119, 2022 05 10.
Article em En | MEDLINE | ID: mdl-35500114
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Alfa-Macroglobulinas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Alfa-Macroglobulinas Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article