Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure.

Bohnsack, John Peyton; Zhang, Huaibo; Wandling, Gabriela M; He, Donghong; Kyzar, Evan J; Lasek, Amy W; Pandey, Subhash C

Bohnsack, John Peyton; Zhang, Huaibo; Wandling, Gabriela M; He, Donghong; Kyzar, Evan J; Lasek, Amy W; Pandey, Subhash C.

Afiliação

Bohnsack JP; Center for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Zhang H; Center for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Wandling GM; Jesse Brown VA Medical Center, Chicago, IL 60612, USA.
He D; Center for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Kyzar EJ; Center for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Lasek AW; Center for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Pandey SC; Center for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL 60612, USA.

Sci Adv ; 8(18): eabn2748, 2022 05 06.

Article em En | MEDLINE | ID: mdl-35507645

Assuntos

Alcoolismo; Epigenômica; Adolescente; Alcoolismo/genética; Animais; Ansiedade/genética; Etanol/efeitos adversos; Histonas/metabolismo; Humanos; Ratos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alcoolismo / Epigenômica Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adolescent / Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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