Peroxynitrous acid-modified extracellular matrix alters gene and protein expression in human coronary artery smooth muscle cells and induces a pro-inflammatory phenotype.

Jørgensen, Sara M; Lorentzen, Lasse G; Chuang, Christine Y; Davies, Michael J

Jørgensen, Sara M; Lorentzen, Lasse G; Chuang, Christine Y; Davies, Michael J.

Afiliação

Jørgensen SM; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark.
Lorentzen LG; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark.
Chuang CY; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark.
Davies MJ; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark. Electronic address: davies@sund.ku.dk.

Free Radic Biol Med ; 186: 43-52, 2022 06.

Article em En | MEDLINE | ID: mdl-35526806

Assuntos

Aterosclerose; Ácido Peroxinitroso; Aterosclerose/metabolismo; Vasos Coronários/metabolismo; Matriz Extracelular/metabolismo; Humanos; Miócitos de Músculo Liso/metabolismo; Oxidantes/metabolismo; Oxirredução; Ácido Peroxinitroso/metabolismo; Fenótipo; Molécula 1 de Adesão de Célula Vascular/metabolismo

Palavras-chave

3-Nitrotyrosine; Extracellular matrix; Peroxynitrite; Protein oxidation; Smooth muscle cell; Versican

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Peroxinitroso / Aterosclerose Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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