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NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition.
Drosos, Yiannis; Myers, Jacquelyn A; Xu, Beisi; Mathias, Kaeli M; Beane, Emma C; Radko-Juettner, Sandi; Mobley, Robert J; Larsen, Margaret E; Piccioni, Federica; Ma, Xiaotu; Low, Jonathan; Hansen, Baranda S; Peters, Samuel T; Bhanu, Natarajan V; Dhanda, Sandeep K; Chen, Taosheng; Upadhyaya, Santhosh A; Pruett-Miller, Shondra M; Root, David E; Garcia, Benjamin A; Partridge, Janet F; Roberts, Charles W M.
Afiliação
  • Drosos Y; Division of Molecular Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Myers JA; Division of Molecular Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Xu B; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Mathias KM; Division of Molecular Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Beane EC; Division of Molecular Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Radko-Juettner S; Division of Molecular Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA; St. Jude Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Mobley RJ; Division of Molecular Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Larsen ME; Division of Molecular Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Piccioni F; Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Ma X; Department of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Low J; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Hansen BS; Center for Advanced Genome Engineering, Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Peters ST; Center for Advanced Genome Engineering, Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Bhanu NV; Department of Biochemistry and Biophysics, Smilow Center for Translational Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Dhanda SK; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Chen T; Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Upadhyaya SA; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Pruett-Miller SM; Center for Advanced Genome Engineering, Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Root DE; Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Garcia BA; Department of Biochemistry and Biophysics, Smilow Center for Translational Research, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Partridge JF; Division of Molecular Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Roberts CWM; Division of Molecular Oncology, Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA; St. Jude Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA. Electronic address: charles.roberts@stjude.org.
Mol Cell ; 82(13): 2472-2489.e8, 2022 07 07.
Article em En | MEDLINE | ID: mdl-35537449
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histona-Lisina N-Metiltransferase / Proteínas F-Box / Histona Desmetilases com o Domínio Jumonji / Proteínas do Grupo Polycomb / Proteína Potenciadora do Homólogo 2 de Zeste / Proteína SMARCB1 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histona-Lisina N-Metiltransferase / Proteínas F-Box / Histona Desmetilases com o Domínio Jumonji / Proteínas do Grupo Polycomb / Proteína Potenciadora do Homólogo 2 de Zeste / Proteína SMARCB1 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article