A small molecule targeting glutathione activates Nrf2 and inhibits cancer cell growth through promoting Keap-1 <i>S</i>-glutathionylation and inducing apoptosis.

Wang, LiHong; Qu, GuoJing; Gao, YuanDi; Su, Le; Ye, Qing; Jiang, Fan; Zhao, BaoXiang; Miao, JunYing

A small molecule targeting glutathione activates Nrf2 and inhibits cancer cell growth through promoting Keap-1 S-glutathionylation and inducing apoptosis.

Wang, LiHong; Qu, GuoJing; Gao, YuanDi; Su, Le; Ye, Qing; Jiang, Fan; Zhao, BaoXiang; Miao, JunYing.

Afiliação

Wang L; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University Jinan 250100 China miaojy@sdu.edu.cn +86 531 88565610 +86 531 88364929.
Qu G; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University Jinan 250100 China miaojy@sdu.edu.cn +86 531 88565610 +86 531 88364929.
Gao Y; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University Jinan 250100 China miaojy@sdu.edu.cn +86 531 88565610 +86 531 88364929.
Su L; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University Jinan 250100 China miaojy@sdu.edu.cn +86 531 88565610 +86 531 88364929.
Ye Q; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese Ministry of Health, Qilu Hospital, Shandong University Jinan 250012 China.
Jiang F; The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese Ministry of Health, Qilu Hospital, Shandong University Jinan 250012 China.
Zhao B; Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University Jinan 250100 China.
Miao J; Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology, School of Life Science, Shandong University Jinan 250100 China miaojy@sdu.edu.cn +86 531 88565610 +86 531 88364929.

RSC Adv ; 8(2): 792-804, 2018 Jan 02.

Article em En | MEDLINE | ID: mdl-35538996

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article