Hyperoside: A Review of Its Structure, Synthesis, Pharmacology, Pharmacokinetics and Toxicity.
Molecules
; 27(9)2022 May 07.
Article
em En
| MEDLINE
| ID: mdl-35566359
ABSTRACT
Hyperoside is an active ingredient in plants, such as Hypericum monogynum in Hypericaceae, Crataegus pinnatifida in Rosaceae and Polygonum aviculare in Polygonaceae. Its pharmacologic effects include preventing cancer and protecting the brain, neurons, heart, kidneys, lung, blood vessels, bones, joints and liver, among others. Pharmacokinetic analysis of hyperoside has revealed that it mainly accumulates in the kidney. However, long-term application of high-dose hyperoside should be avoided in clinical practice because of its renal toxicity. This review summarises the structure, synthesis, pharmacology, pharmacokinetics and toxicity of hyperoside.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hypericum
/
Polygonum
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Crataegus
Idioma:
En
Ano de publicação:
2022
Tipo de documento:
Article