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A first-in-human Phase I dose-escalation trial of the novel therapeutic peptide, ALM201, demonstrates a favourable safety profile in unselected patients with ovarian cancer and other advanced solid tumours.
El Helali, Aya; Plummer, Ruth; Jayson, Gordon C; Coyle, Vicky M; Drew, Yvette; Mescallado, Nerissa; Harris, Noor; Clamp, Andrew R; McCann, Janine; Swaisland, Helen; Kennedy, Richard D; Cranston, Aaron N; Wilson, Richard H.
Afiliação
  • El Helali A; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • Plummer R; University of Hong Kong, 21 Sassoon Road, Pok Fu Lam, Hong Kong.
  • Jayson GC; Newcastle University Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Coyle VM; Institute of Cancer Sciences and Christie Hospital, University of Manchester, Manchester, UK.
  • Drew Y; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • Mescallado N; Newcastle University Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
  • Harris N; Institute of Cancer Sciences and Christie Hospital, University of Manchester, Manchester, UK.
  • Clamp AR; Newcastle University Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
  • McCann J; Institute of Cancer Sciences and Christie Hospital, University of Manchester, Manchester, UK.
  • Swaisland H; Northern Ireland Cancer Research Consumers' Forum, Belfast, UK.
  • Kennedy RD; Therakin Consulting Ltd., Sandbach, UK.
  • Cranston AN; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, UK.
  • Wilson RH; Almac Diagnostic Services, Craigavon, UK.
Br J Cancer ; 127(1): 92-101, 2022 07.
Article em En | MEDLINE | ID: mdl-35568736
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias / Antineoplásicos Limite: Female / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias / Antineoplásicos Limite: Female / Humans / Male Idioma: En Ano de publicação: 2022 Tipo de documento: Article