5-hmC loss is another useful tool in addition to BAP1 and MTAP immunostains to distinguish diffuse malignant peritoneal mesothelioma from reactive mesothelial hyperplasia in peritoneal cytology cell-blocks and biopsies.

Alsugair, Ziyad; Kepenekian, Vahan; Fenouil, Tanguy; Glehen, Olivier; Villeneuve, Laurent; Isaac, Sylvie; Hommell-Fontaine, Juliette; Benzerdjeb, Nazim

Alsugair, Ziyad; Kepenekian, Vahan; Fenouil, Tanguy; Glehen, Olivier; Villeneuve, Laurent; Isaac, Sylvie; Hommell-Fontaine, Juliette; Benzerdjeb, Nazim.

Afiliação

Alsugair Z; Department of Pathology, Institut de Pathologie Multisite, Groupement Hospitalier Sud, Hospices Civils de Lyon, 165 chemin du Grand-Revoyet, 69310, Pierre-Bénite, France.
Kepenekian V; Department of Digestive Surgery, Lyon University Hospital, Pierre-Bénite, France.
Fenouil T; EA 3738 CICLY, Lyon 1 University, Lyon, France.
Glehen O; French Network for Rare Peritoneal Tumors (RENAPE), Villeurbanne, France.
Villeneuve L; Department of Pathology, Institut de Pathologie Multisite, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France.
Isaac S; Department of Digestive Surgery, Lyon University Hospital, Pierre-Bénite, France.
Hommell-Fontaine J; EA 3738 CICLY, Lyon 1 University, Lyon, France.
Benzerdjeb N; French Network for Rare Peritoneal Tumors (RENAPE), Villeurbanne, France.

Virchows Arch ; 481(1): 23-29, 2022 Jul.

Article em En | MEDLINE | ID: mdl-35575935

Assuntos

Neoplasias Pulmonares; Mesotelioma Maligno; Mesotelioma; Neoplasias Peritoneais; Neoplasias Pleurais; Biomarcadores Tumorais/análise; Biópsia; Diagnóstico Diferencial; Humanos; Hiperplasia/diagnóstico; Imuno-Histoquímica; Hibridização in Situ Fluorescente; Neoplasias Pulmonares/patologia; Mesotelioma/diagnóstico; Mesotelioma/patologia; Mesotelioma Maligno/diagnóstico; Neoplasias Peritoneais/diagnóstico; Neoplasias Pleurais/diagnóstico; Purina-Núcleosídeo Fosforilase; Proteínas Supressoras de Tumor/genética; Ubiquitina Tiolesterase/genética

Palavras-chave

5-hmC; Biomarker; Diffuse malignant peritoneal mesothelioma; Mesothelioma; Reactive mesothelial hyperplasia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Peritoneais / Neoplasias Pleurais / Mesotelioma Maligno / Neoplasias Pulmonares / Mesotelioma Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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