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Protein lifetimes in aged brains reveal a proteostatic adaptation linking physiological aging to neurodegeneration.
Kluever, Verena; Russo, Belisa; Mandad, Sunit; Kumar, Nisha Hemandhar; Alevra, Mihai; Ori, Alessandro; Rizzoli, Silvio O; Urlaub, Henning; Schneider, Anja; Fornasiero, Eugenio F.
Afiliação
  • Kluever V; Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, 37073 Göttingen, Germany.
  • Russo B; German Center for Neurodegenerative Diseases, DZNE Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
  • Mandad S; Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, 37073 Göttingen, Germany.
  • Kumar NH; Department of Clinical Chemistry, University Medical Center Göttingen, 37077 Göttingen, Germany.
  • Alevra M; Bioanalytical Mass Spectrometry Group, Max Planck Institute for Multidisciplinary Sciences, 37077 Göttingen, Germany.
  • Ori A; Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, 37073 Göttingen, Germany.
  • Rizzoli SO; Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, 37073 Göttingen, Germany.
  • Urlaub H; Leibniz Institute on Aging-Fritz Lipmann Institute (FLI), 07745 Jena, Germany.
  • Schneider A; Department of Neuro- and Sensory Physiology, University Medical Center Göttingen, 37073 Göttingen, Germany.
  • Fornasiero EF; Department of Clinical Chemistry, University Medical Center Göttingen, 37077 Göttingen, Germany.
Sci Adv ; 8(20): eabn4437, 2022 05 20.
Article em En | MEDLINE | ID: mdl-35594347
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Doenças Neurodegenerativas Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Envelhecimento / Doenças Neurodegenerativas Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article