Enantioseparation of N-methyl duloxetine, duloxetine, and fluoxetine by countercurrent chromatography using anionic ß-cyclodextrin as chiral selector.

Sun, Wenyu; Chen, Ben; You, Haibo; Fang, Liqun; Qian, Junqing; Tong, Shengqiang

Sun, Wenyu; Chen, Ben; You, Haibo; Fang, Liqun; Qian, Junqing; Tong, Shengqiang.

Afiliação

Sun W; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, P. R. China.
Chen B; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, P. R. China.
You H; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, P. R. China.
Fang L; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, P. R. China.
Qian J; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, P. R. China.
Tong S; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, P. R. China.

J Sep Sci ; 45(15): 3022-3030, 2022 Aug.

Article em En | MEDLINE | ID: mdl-35598113

Assuntos

Distribuição Contracorrente; beta-Ciclodextrinas; Ânions; Distribuição Contracorrente/métodos; Cloridrato de Duloxetina/análogos & derivados; Éteres; Fluoxetina; Fosfatos; Solventes; Estereoisomerismo; beta-Ciclodextrinas/química

Palavras-chave

anionic ß-cyclodextrins; antidepressant; countercurrent chromatography; enantioseparation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Distribuição Contracorrente / Beta-Ciclodextrinas Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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