The Attenuated Pseudorabies Virus Vaccine Strain Bartha Hyperactivates Plasmacytoid Dendritic Cells by Generating Large Amounts of Cell-Free Virus in Infected Epithelial Cells.

Delva, Jonas L; Van Waesberghe, Cliff; Van Den Broeck, Wim; Lamote, Jochen A; Vereecke, Nick; Theuns, Sebastiaan; Couck, Liesbeth; Favoreel, Herman W

Delva, Jonas L; Van Waesberghe, Cliff; Van Den Broeck, Wim; Lamote, Jochen A; Vereecke, Nick; Theuns, Sebastiaan; Couck, Liesbeth; Favoreel, Herman W.

Afiliação

Delva JL; Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Ghent, Belgium.
Van Waesberghe C; Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Ghent, Belgium.
Van Den Broeck W; Department of Morphology, Imaging, Orthopedics, Rehabilitation and Nutrition, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Ghent, Belgium.
Lamote JA; VIB-KULeuven Center for Cancer Biology, VIB FACS Expertise Center, Leuven, Belgium.
Vereecke N; Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Ghent, Belgium.
Theuns S; Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Ghent, Belgium.
Couck L; Department of Morphology, Imaging, Orthopedics, Rehabilitation and Nutrition, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Ghent, Belgium.
Favoreel HW; Department of Translational Physiology, Infectiology and Public Health, Faculty of Veterinary Medicine, Ghent Universitygrid.5342.0, Ghent, Belgium.

J Virol ; 96(12): e0219921, 2022 06 22.

Article em En | MEDLINE | ID: mdl-35604216

Assuntos

Células Dendríticas; Herpesvirus Suídeo 1; Pseudorraiva; Doenças dos Suínos; Animais; Células Dendríticas/imunologia; Herpesvirus Suídeo 1/genética; Imunogenicidade da Vacina; Pseudorraiva/prevenção & controle; Vacinas contra Pseudorraiva/genética; Suínos; Doenças dos Suínos/prevenção & controle; Vacinas Atenuadas; Proteínas do Envelope Viral/genética

Palavras-chave

Aujeszky's disease virus; Bartha; Bartha-K61; PRV; US2; gE/gI; glycoprotein E; glycoprotein I; interferon; pDC; plasmacytoid dendritic cell; plasmacytoid dendritic cells; pseudorabies virus; suid herpesvirus 1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pseudorraiva / Doenças dos Suínos / Células Dendríticas / Herpesvirus Suídeo 1 Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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