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Highly polymerized proanthocyanidins (PAC) components from blueberry leaf and stem significantly inhibit SARS-CoV-2 infection via inhibition of ACE2 and viral 3CLpro enzymes.
Sugamoto, Kazuhiro; Tanaka, Yuri L; Saito, Akatsuki; Goto, Yoh; Nakayama, Takayuki; Okabayashi, Tamaki; Kunitake, Hisato; Morishita, Kazuhiro.
Afiliação
  • Sugamoto K; Department of Applied Chemistry, Faculty of Engineering, University of Miyazaki, Japan. Electronic address: kmorishi@med.miyazaki-u.ac.jp.
  • Tanaka YL; Department of Veterinary Sciences, Faculty of Agriculture, University of Miyazaki, Japan.
  • Saito A; Department of Veterinary Sciences, Faculty of Agriculture, University of Miyazaki, Japan; Center for Animal Disease Control, University of Miyazaki, Japan.
  • Goto Y; Biolabo Co.,Ltd, Kobe, Hyogo, Japan.
  • Nakayama T; Biolabo Co.,Ltd, Kobe, Hyogo, Japan.
  • Okabayashi T; Department of Veterinary Sciences, Faculty of Agriculture, University of Miyazaki, Japan; Center for Animal Disease Control, University of Miyazaki, Japan.
  • Kunitake H; Department of Biochemistry and Applied Biosciences, Faculty of Agriculture, University of Miyazaki, Japan.
  • Morishita K; HTLV-1/ATL Research, Education and Medical Facility, Faculty of Medicine, University of Miyazaki, Japan; Project for Advanced Medical Research and Development, Project Research Division, Frontier Science Research Center, University of Miyazaki, University of Miyazaki, Japan.
Biochem Biophys Res Commun ; 615: 56-62, 2022 07 30.
Article em En | MEDLINE | ID: mdl-35605406
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mirtilos Azuis (Planta) / Proantocianidinas / Tratamento Farmacológico da COVID-19 Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mirtilos Azuis (Planta) / Proantocianidinas / Tratamento Farmacológico da COVID-19 Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article