Mediating EGFR-TKI Resistance by VEGF/VEGFR Autocrine Pathway in Non-Small Cell Lung Cancer.

Osude, Chike; Lin, Leo; Patel, Meet; Eckburg, Adam; Berei, Joseph; Kuckovic, Adijan; Dube, Namrata; Rastogi, Aayush; Gautam, Shruti; Smith, Thomas J; Sreenivassappa, Shylendra B; Puri, Neelu

Osude, Chike; Lin, Leo; Patel, Meet; Eckburg, Adam; Berei, Joseph; Kuckovic, Adijan; Dube, Namrata; Rastogi, Aayush; Gautam, Shruti; Smith, Thomas J; Sreenivassappa, Shylendra B; Puri, Neelu.

Afiliação

Osude C; Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA.
Lin L; Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA.
Patel M; Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA.
Eckburg A; Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA.
Berei J; Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA.
Kuckovic A; Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA.
Dube N; Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA.
Rastogi A; Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA.
Gautam S; Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA.
Smith TJ; College of Education, Northern Illinois University, Dekalb, IL 60115, USA.
Sreenivassappa SB; Department of Hematology/Oncology, OSF Saint Anthony Medical Center, Rockford, IL 61107, USA.
Puri N; Department of Biomedical Sciences, University of Illinois College of Medicine at Rockford, Rockford, IL 61107, USA.

Cells ; 11(10)2022 05 19.

Article em En | MEDLINE | ID: mdl-35626731

Assuntos

Carcinoma Pulmonar de Células não Pequenas; Neoplasias Pulmonares; Receptores de Fatores de Crescimento do Endotélio Vascular/metabolismo; Carcinoma Pulmonar de Células não Pequenas/tratamento farmacológico; Carcinoma Pulmonar de Células não Pequenas/genética; Carcinoma Pulmonar de Células não Pequenas/metabolismo; Linhagem Celular Tumoral; Resistencia a Medicamentos Antineoplásicos; Receptores ErbB/metabolismo; Cloridrato de Erlotinib/farmacologia; Cloridrato de Erlotinib/uso terapêutico; Humanos; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Mutação/genética; Inibidores de Proteínas Quinases/farmacologia; Inibidores de Proteínas Quinases/uso terapêutico; Fator A de Crescimento do Endotélio Vascular/genética; Receptor 2 de Fatores de Crescimento do Endotélio Vascular/genética; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

epidermal growth factor receptor (EGFR); neuropilin-1 (NP-1); non-small cell lung cancer (NSCLC); survival analysis; tumors; tyrosine kinase inhibitor (TKI); vascular endothelial growth factor (VEGF); vascular endothelial growth factor receptor-2 (VEGFR-2)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Receptores de Fatores de Crescimento do Endotélio Vascular / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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